SISTEMATIK REVIEW DAN ANALISIS BIBLIOGRAFI HERBAL DALAM TERAPI COVID-19 DI ERA PANDEMI

azis ikhsanudin, Salma Kumala Dewi, Khapita Nurin Nirmala, Lolita Lolita

Abstract


Latar belakang: Covid-19 merupakan penyakit pernapasan akut yang menjadi pandemi di seluruh dunia.

Tujuan: Penelitian ini bertujuan untuk menganalisis struktur tematik dan tren dalam publikasi ilmiah yang membahas tentang penggunaan herbal dalam terapi covid-19 dan memberikan peta jalan untuk penelitian masa depan.

Metode: Penelitian ini menggunakan sistematik literature review (SLR) dan bibliometric analysis (BA) untuk mendeskripsikan tanaman obat atau herbal dalam terapi covid-19 serta mengungkap profil bibliometriknya. Data diperoleh dari database Scopus 2020–2023 tentang penelitian penggunaan herbal dalam terapi covid-19. Kata kunci yang digunakan ("Herbal" AND "Drug" AND “Covid-19” AND “Therapy” OR “Treatment”)

Hasil: Studi ini menemukan bahwa sebagian besar artikel tentang penggunaan herbal dalam terapi covid-19 membahas tentang sarcov-2, pengobatan tradisional Cina, pengobatan herbal Cina. Hasil menunjukkan struktur dan tren studi pengobatan herbal, negara Cina mendominasi dalam pengembangan pengobatan herbal untuk covid-19. Data penelitian pengembangan herbal dalam terapi covid-19 di Asia Tenggara baru negara Filipina yang melakukan pengembangan penelitian herbal untuk covid-19. Oleh karena itu, pengembangan herbal atau obat tradisional dalam terapi covid-19 masih memiliki peluang besar untuk dikembangkan terlebih herbal di Asia Tenggara khususnya herbal Indonesia.

Kesimpulan: Artikel ini berusaha untuk mendapatkan wawasan penelitian tentang pengobatan covid-19 berbasis herbal telah dikembangkan baik secara pre-klinis maupun klinis menggunakan tinjauan literatur sistematis dan analisis bibliometrik.

Kata kunci: Bibliometrik, covid-19, herbal, systematic review, terapi


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References


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Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol. 2014 Jan;4:177.

Ang L, Song E, Lee HW, Lee MS. Herbal Medicine for the Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Clin Med. 2020 May;9(5).

Koshak AE, Koshak EA, Mobeireek AF, Badawi MA, Wali SO, Malibary HM, et al. Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial. Complement Ther Med [Internet]. 2021;61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113589877&doi=10.1016%2Fj.ctim.2021.102769&partnerID=40&md5=9c8dd6dc89d56d4e9b6091c9e738ba2a

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GÜLHAN P, Kurutkan MN. Bibliometric Analysis of COVID-19 Publications in the Field of Chest and Infectious Diseases. Düzce Tıp Fakültesi Derg. 2021 Mar;23.

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Abubakar IB, Kankara SS, Malami I, Danjuma JB, Muhammad YZ, Yahaya H, et al. Traditional medicinal plants used for treating emerging and re-emerging viral diseases in northern Nigeria. Eur J Integr Med [Internet]. 2022;49. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121232907&doi=10.1016%2Fj.eujim.2021.102094&partnerID=40&md5=03ed5e81a9a1a8c0037ad11800a081c4

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Shi N, Guo L, Liu B, Bian Y, Chen R, Chen S, et al. Efficacy and safety of Chinese herbal medicine versus Lopinavir-Ritonavir in adult patients with coronavirus disease 2019: A non-randomized controlled trial. Phytomedicine [Internet]. 2021;81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096858746&doi=10.1016%2Fj.phymed.2020.153367&partnerID=40&md5=90fc9ff99433169e73fd1073d65fadf5

Jan J-T, Cheng T-JR, Juang Y-P, Ma H-H, Wu Y-T, Yang W-B, et al. Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection. Proc Natl Acad Sci U S A [Internet]. 2021;118(5). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100037906&doi=10.1073%2Fpnas.2021579118&partnerID=40&md5=d858082ac9a09c490f8a055b7fad9269

Dilip Pandkar P, Deshmukh SR, Sachdeva V. COVID-19 patient with B cell lymphoma co-morbidity managed with co-administration of ayurvedic formulation. J Ayurveda Integr Med [Internet]. 2022;13(3). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137334049&doi=10.1016%2Fj.jaim.2022.100632&partnerID=40&md5=7dcef2e39c886adcd8620637fec03c94

Chaachouay N, Douira A, Zidane L. COVID-19, prevention and treatment with herbal medicine in the herbal markets of Salé Prefecture, North-Western Morocco. Eur J Integr Med [Internet]. 2021;42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100105998&doi=10.1016%2Fj.eujim.2021.101285&partnerID=40&md5=81c5b07bd6e6d5f1ae0aa23db785b423

An Y-W, Yuan B, Wang J-C, Wang C, Liu T-T, Song S, et al. Clinical characteristics and impacts of traditional chinese medicine treatment on the convalescents of covid-19. Int J Med Sci [Internet]. 2021;18(3):646–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099281809&doi=10.7150%2Fijms.52664&partnerID=40&md5=02af15e60acda937c2076e0c0ff44fb3

Chen G, Su W, Yang J, Luo D, Xia P, Jia W, et al. Chinese herbal medicine reduces mortality in patients with severe and critical Coronavirus disease 2019: a retrospective cohort study. Front Med [Internet]. 2020;14(6):752–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091021878&doi=10.1007%2Fs11684-020-0813-6&partnerID=40&md5=be9c82dfd98b35c5a99308c4cc7737b6

Sharma A, Tiwari S, Deb MK, Marty JL. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies. Int J Antimicrob Agents. 2020 Aug;56(2):106054.

Wang J, Du G. COVID-19 may transmit through aerosol. Ir J Med Sci. 2020 Nov;189(4):1143–4.

World Health Organization. WHO Coronavirus Disease (COVID-19) Dashboard With Vaccination Data | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data [Internet]. World Health Organization. 2022. p. 1–5. Available from: https://covid19.who.int/%0Ahttps://covid19.who.int/%0Ahttps://covid19.who.int/region/searo/country/bd

Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol. 2014 Jan;4:177.

Ang L, Song E, Lee HW, Lee MS. Herbal Medicine for the Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Clin Med. 2020 May;9(5).

Koshak AE, Koshak EA, Mobeireek AF, Badawi MA, Wali SO, Malibary HM, et al. Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial. Complement Ther Med [Internet]. 2021;61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113589877&doi=10.1016%2Fj.ctim.2021.102769&partnerID=40&md5=9c8dd6dc89d56d4e9b6091c9e738ba2a

Feng J, Zhou S, Xie Q, Huang T, Xu X, Zhou D, et al. Traditional Chinese medicine shenhuang granule in patients with severe/critical COVID-19: A randomized controlled multicenter trial. Phytomedicine [Internet]. 2021;89. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107831415&doi=10.1016%2Fj.phymed.2021.153612&partnerID=40&md5=0a085971b26d6702fb2084ef8ab078a4

Yu Y, Li Y, Zhang Z, Gu Z, Zhong H, Zha Q, et al. A bibliometric analysis using VOSviewer of publications on COVID-19. Ann Transl Med. 2020 Jul;8(13):816.

Zupic I, Čater T. Bibliometric methods in management and organization. Organ Res Methods. 2015 Jul;18:429–72.

GÜLHAN P, Kurutkan MN. Bibliometric Analysis of COVID-19 Publications in the Field of Chest and Infectious Diseases. Düzce Tıp Fakültesi Derg. 2021 Mar;23.

Donthu N, Kumar S, Mukherjee D, Pandey N, Lim WM. How to conduct a bibliometric analysis: An overview and guidelines. J Bus Res. 2021;133:285–96.

Abubakar IB, Kankara SS, Malami I, Danjuma JB, Muhammad YZ, Yahaya H, et al. Traditional medicinal plants used for treating emerging and re-emerging viral diseases in northern Nigeria. Eur J Integr Med [Internet]. 2022;49. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121232907&doi=10.1016%2Fj.eujim.2021.102094&partnerID=40&md5=03ed5e81a9a1a8c0037ad11800a081c4

Ding J, Liu W, Guan H, Feng Y, Bao Y, Li H, et al. Corrected QT interval in hospitalized patients with coronavirus disease 2019: Focus on drugs therapy. Med (United States) [Internet]. 2021;100(28). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111747620&doi=10.1097%2FMD.0000000000026538&partnerID=40&md5=96cbedce28ff32587e44f66d09e6afd8

Kamalinejad M, Sarmadian H, Shokouhi F, Dadmehr M, Bahrami M, Dehnad A, et al. The Clinical Efficacy of Tiban Syrup as Adjuvant Treatment in Patients with COVID-19: A Randomized, Double-Blind Clinical Trial. Iran J Pharm Sci [Internet]. 2021;17(3):49–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125256439&doi=10.22034%2FIJPS.2021.541704.1934&partnerID=40&md5=0c6c6e9456a315fe37f6e582f50cd5f3

Liu J, Jiang Y, Liu Y, Pu L, Du C, Li Y, et al. Yindan Jiedu Granules, a Traditional Chinese Medicinal Formulation, as a Potential Treatment for Coronavirus Disease 2019. Front Pharmacol [Internet]. 2021;11. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101141126&doi=10.3389%2Ffphar.2020.634266&partnerID=40&md5=e11dcce1381dc430245ce8407a7a2f81

Shi N, Guo L, Liu B, Bian Y, Chen R, Chen S, et al. Efficacy and safety of Chinese herbal medicine versus Lopinavir-Ritonavir in adult patients with coronavirus disease 2019: A non-randomized controlled trial. Phytomedicine [Internet]. 2021;81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096858746&doi=10.1016%2Fj.phymed.2020.153367&partnerID=40&md5=90fc9ff99433169e73fd1073d65fadf5

Jan J-T, Cheng T-JR, Juang Y-P, Ma H-H, Wu Y-T, Yang W-B, et al. Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection. Proc Natl Acad Sci U S A [Internet]. 2021;118(5). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100037906&doi=10.1073%2Fpnas.2021579118&partnerID=40&md5=d858082ac9a09c490f8a055b7fad9269

Dilip Pandkar P, Deshmukh SR, Sachdeva V. COVID-19 patient with B cell lymphoma co-morbidity managed with co-administration of ayurvedic formulation. J Ayurveda Integr Med [Internet]. 2022;13(3). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137334049&doi=10.1016%2Fj.jaim.2022.100632&partnerID=40&md5=7dcef2e39c886adcd8620637fec03c94

Chaachouay N, Douira A, Zidane L. COVID-19, prevention and treatment with herbal medicine in the herbal markets of Salé Prefecture, North-Western Morocco. Eur J Integr Med [Internet]. 2021;42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100105998&doi=10.1016%2Fj.eujim.2021.101285&partnerID=40&md5=81c5b07bd6e6d5f1ae0aa23db785b423

An Y-W, Yuan B, Wang J-C, Wang C, Liu T-T, Song S, et al. Clinical characteristics and impacts of traditional chinese medicine treatment on the convalescents of covid-19. Int J Med Sci [Internet]. 2021;18(3):646–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099281809&doi=10.7150%2Fijms.52664&partnerID=40&md5=02af15e60


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